Macroscale Collagen‐Actomyosin Hybrid Actuator Built from Bioderived Materials

Abstract Biological muscles mainly consist of motor proteins that play essential roles and have a hierarchical structure covered with collagen can transmit the tension to bones via tendons. The artificial reconstruction is highly expected from viewpoint engineering biology. Although been developed synthetic biological molecular motors, there considerable gap between components muscles, resulting in significant obstacle further scale‐up force transfer through macroscale structures. To overcome these obstacles bioderived biomolecules, this study proposes collagen‐actomyosin hybrid soft actuator inspired by muscles. Collagen gel entrapping actomyosin maintaining actuator's shape transmitting tensile force. generated forces reach micro‐newton range, enabling actuation millimeter‐scale mechanical components. These properties may be helpful for fabrication robotic systems advanced functionalities.